Unlocking the Power of Cationic Polymers: Insights, Applications, and Innovations
Cationic Polymers: Guiding DNA to the Nucleus
Cationic polymers form protective polyplexes with DNA, enabling cellular entry, endosomal escape, and nuclear delivery for gene expression. This process enhances DNA stability and efficiency in gene transfer applications.
Hydrolysable cationic polymers have been explored as non-viral gene delivery vectors due to their lower toxicity compared to non-degradable alternatives. Over the past decade, research on these polymers has contributed to the development of more efficient and adaptable nucleic acid delivery systems.
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